The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago.Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets.As a better understanding of MMP biology and inhibitor pharmacokinetic properties emerged, it became clear that initial MMP inhibitor clinical trials

Multi-spectral photometric stereo can recover pixel-wise surface normal from a single RGB image.The difficulty lies in that the intensity in each channel is the tangle of illumination, albedo and camera response; thus, Bags - Patient Belongings Bags and Boxes an initial estimate of the normal is required in optimization-based solutions.In this pape

The Frasassi caves, located in the Sentino River Gorge in Ancona Province (Marche, Italy), contains boxwork in a small zone in the inner part of the cave system where it is closely associated with subaqueous corrosion produced by sulfuric acid speleogenesis.The boxwork consists of barite that replaces calcite spar-filled veins and Pepper Shakers li

Water distribution systems are one of the critical infrastructures and major assets of the water utility in a nation.The infrastructure of the Sanitizer Dispensers distribution systems consists of resources, treatment plants, reservoirs, distribution lines, and consumers.A sustainable water distribution network management has to take care of access